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Tofacitinib Citrate CAS 540737-29-9Tofacitinib Citrate CAS 540737-29-9, is a Janus kinase (JAK) inhibitor that is administered orally and has immunomodulatory and anti-inflammatory effects. It is a citrate formed by combining...read more
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Ademetionine 1 4 Butanedisulfonate CAS 101020-79-5Ademetionine 1 4 Butanedisulfonate CAS 101020-79-5, is a stabilized pharmaceutical form of SAMe, primarily used for cholestatic liver diseases, depression, and osteoarthritis. It acts as a methyl...read more
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Benserazide Hydrochloride CAS 14919-77-8Benserazide Hydrochloride CAS 14919-77-8, is a peripheral aromatic L-amino acid decarboxylase (AADC) inhibitor. It is not used as a standalone therapeutic agent but is almost exclusively combined...read more
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Dotinurad CAS 1285572-51-1Dotinurad CAS 1285572-51-1, is a novel selective urate reabsorption inhibitor (SURI) used for the treatment of hyperuricemia and gout.read more
Indications: Hyperuricemia -
Elsulfavirine Potassium CAS 868046-19-9Elsulfavirine Potassium CAS 868046-19-9, is a new generation non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat human immunodeficiency virus type 1 (HIV-1)...read more
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Lemborexant CAS 1369764-02-2Lemborexant CAS 1369764-02-2, is a Sleep Initiation and Maintenance Disorders drug used for treatment of adult insomnia characterized by difficulty falling asleep and/or maintaining sleep.read more
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Lorundrostat CAS 1820940-17-7Lorundrostat CAS 1820940-17-7, is a inhibitor of aldosterone synthase (CYP11B2). Drug candidate for the treatment of hypertension and primary aldosteronism.read more
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Mirdametinib CAS 391210-10-9Mirdametinib CAS 391210-10-9, PD0325901, is a MEK inhibitor and has been approved for the treatment of Neurofibromatosis Type 1 (NF1) in USA.read more
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RESMETIROM CAS 920509-32-6RESMETIROM CAS 920509-32-6, is a thyroid hormone receptor beta agonist, treatment of Metabolic Dysfunction Associated Steatotic Liver Disease.read more
Tofacitinib citrate is a white to off-white crystalline powder insoluble in water and ethanol but very soluble in DMSO and N, N-Dimethylacetamide. It is the first oral JAK inhibitor in history ever...
Apr 16, 2019 · Additionally, our findings demonstrate that tofacitinib citrate can successfully be nebulized at a suitable droplet size for inhalation (1.2 ± 0.2 μm MMAD) through a nose-only...
We report a case of generalized vitiligo for which treatment with tofacitinib citrate, an oral Janus kinase 1/3 inhibitor, resulted in significant repigmentation. Conclusions and relevance: The...
Apr 06, 2022 · Tofacitinib is a prescription medication called a janus kinase (JAK) inhibitor. It is a disease modifying anti-rheumatic drug (DMARD), which works by suppressing the immune...
Tofacitinib (Xeljanz) is an oral drug used to treat adults with moderately to severely active rheumatoid arthritis (RA) in cases where methotrexate did not work well. Tofacitinib works by...
Tofacitinib is a potent, cell-permeable inhibitor of all JAK isoforms (IC 50 s = 6.1, 12, and 8 nM for JAK1, JAK2, and JAK3, respectively). 1 It is selective for JAK1-3 over ROCK2 and Lck (IC 50 s =...
